Exchange 2010 – Single Common Name SSL Certificate

Create SRV record:
Service: _autodiscover
Protocol: _tcp
Port Number: 443
Host: mail.example.net

$URLName="mail.example.net"
$ComputerName="exch-svr"    
Get-AutodiscoverVirtualDirectory | Set-AutodiscoverVirtualDirectory –InternalUrl "https://$URLName/Autodiscover/Autodiscover.xml"
Get-ClientAccessServer | Set-ClientAccessServer –AutodiscoverServiceInternalUri "https://$URLName/Autodiscover/Autodiscover.xml"
Get-WebservicesVirtualDirectory | Set-WebservicesVirtualDirectory –InternalUrl "https://$URLName/Ews/Exchange.asmx"
Get-OabVirtualDirectory | Set-OabVirtualDirectory –InternalUrl "https://$URLName/Oab"
Get-OwaVirtualDirectory | Set-OwaVirtualDirectory –InternalUrl "https://$URLName/Owa"
Get-EcpVirtualDirectory | Set-EcpVirtualDirectory –InternalUrl "https://$URLName/Ecp"
Get-ActiveSyncVirtualDirectory -Server $ComputerName | Set-ActiveSyncVirtualDirectory -InternalUrl "https://$URLName/Microsoft-Server-ActiveSync"
Get-AutodiscoverVirtualDirectory | Set-AutodiscoverVirtualDirectory –ExternalUrl "https://$URLName/Autodiscover/Autodiscover.xml"
Get-webservicesVirtualDirectory | Set-webservicesVirtualDirectory –ExternalUrl "https://$URLName/Ews/Exchange.asmx"
Get-OabVirtualDirectory | Set-OabVirtualDirectory –ExternalUrl "https://$URLName/Oab"
Get-OwaVirtualDirectory | Set-OwaVirtualDirectory –ExternalUrl "https://$URLName/Owa"
Get-EcpVirtualDirectory | Set-EcpVirtualDirectory –ExternalUrl "https://$URLName/Ecp"
Get-ActiveSyncVirtualDirectory | Set-ActiveSyncVirtualDirectory -ExternalUrl "https://$URLName/Microsoft-Server-ActiveSync"

Run get-exchangecertificate and note the thumbprint on the new certificate (watch out for dublets!)

Run Enable-exchangecertificate -thumbprint <TUMBPRINT> -services SMTP,IIS,POP,IMAP

Run iisreset

Restart the Microsoft Exchange services

Restart Clients Pc’s

source: http://www.cohesivelogic.com/exchange-2010-single-name-ssl-certificates/